A first-degree relative with medullary thyroid cancer is a contraindication. A strong, persistent history in multi-generations outside of a first-degree relative is also a contraindication. Please discuss with the medical provider all relatives diagnosed with medullary thyroid cancer. To date, MTC after GLP-1 administration has been observed only in rodents and not in humans.

Yes. Since GLP-1 slows food transit through the intestines, you may experience nausea, acid reflux, constipation, or diarrhea. We have medication at Options to help with this and can also prescribe medications to your local pharmacy. NOTE: GLP-1 medication may trigger pancreatitis, gallbladder attacks or gastroparesis. Discuss with your medical provider if you have a history of these conditions.

If you have discussed fertility plans or treatments with your doctor, it is recommended to stop GLP-1 medications at least 2 months prior to TTC. Please speak with your physician to determine if a longer washout period is recommended.

Injection training handouts and videos are available to you. You may also request an injection training appointment with our Medical Provider Assistant who can do an in-person or telehealth video appointment to train you in the process. 

Limited data has indicated a small subset patients experience mood changes after the initiation of GLP-1. Please discuss with your medical provider if you do not feel like yourself. If you are having suicidal thoughts, stop the medication immediately and call your medical provider. The Suicide & Crisis Lifeline at 988 is available by phone or text 24/7 for immediate help.

Semaglutide: 15-20% of body weight
Tirzepatide: 20-25% of body weight

May decrease bad cholesterol (LDL)
May decreased blood pressure
May decrease hyperglycemia, Hemoglobin A1c
May decrease or slow progression of pre-diabetes into diabetes mellitus
May improve functional capacity and activities of daily living
May decrease cardiovascular mortality risk by 20%
May decrease progression of chronic kidney disease
May help with psychiatric disorders as currently being studied as a possible treatment for anxiety, depression, addiction, and PTSD

GI upset, headache, fatigue, and dizziness. Most of these symptoms can be minimized with adequate hydration, electrolyte replacement and vitamins. Options has lipotropic injections as well as vitamins, supplements, and stool softeners to help any side effects. Rest may also be helpful. For a headache, acetaminophen or ibuprofen is useful.

Do not stop your diabetes medications right away. Talk to your primary care physician to titrate your medication doses down as your blood sugar and hemoglobin A1c improves.